Acetone, methylene-
Methyl vinyl ketone
CAS: 78-94-4
Molecular Formula: C4H6O
Acetone, methylene- - Names and Identifiers
| Name | Methyl vinyl ketone |
| Synonyms | Butenone 3-buten-2-one But-3-en-2-one acetylethylene Acetyl ethylene Acetyle-thylene delta(3)-2-butenone Acetone, methylene- Methyl vinyl ketone 2,4-dimethylpenta-1,4-dien-3-one |
| CAS | 78-94-4 |
| EINECS | 201-160-6 |
| InChI | InChI=1/C7H10O/c1-5(2)7(8)6(3)4/h1,3H2,2,4H3 |
Acetone, methylene- - Physico-chemical Properties
| Molecular Formula | C4H6O |
| Molar Mass | 70.09 |
| Density | 0.864g/mLat 25°C(lit.) |
| Melting Point | -7°C |
| Boling Point | 80 °C |
| Flash Point | 20°F |
| Water Solubility | MISCIBLE |
| Solubility | Chloroform (Sparingly), Methanol (Slightly) |
| Vapor Presure | 310 mm Hg ( 55 °C) |
| Vapor Density | 1.3 (vs air) |
| Appearance | Liquid |
| Specific Gravity | 0.864 |
| Color | Clear colorless to pale yellow, may discolor to brown on storage |
| Merck | 14,6134 |
| BRN | 506021 |
| Storage Condition | 2-8°C |
| Stability | Stable. Incompatible with strong bases, strong oxidizing agents, strong reducing agents. Heat and light sensitive. May undergo autopolymerization. Highly flammable. Refrigerate. |
| Explosive Limit | 15.64% |
| Refractive Index | n20/D 1.411(lit.) |
| Physical and Chemical Properties | colorless liquid. Boiling point 80.4°C, flash point -8°C, soluble in water, ethanol, etc. |
| Use | As a monomer for polymerization, an ion exchange resin and a drug are produced. |
Acetone, methylene- - Risk and Safety
| Risk Codes | R11 - Highly Flammable R26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed. R34 - Causes burns R43 - May cause sensitization by skin contact R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R26/28 - Very toxic by inhalation and if swallowed. R68 - Possible risk of irreversible effects R40 - Limited evidence of a carcinogenic effect |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S28 - After contact with skin, wash immediately with plenty of soap-suds. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S38 - In case of insufficient ventilation, wear suitable respiratory equipment. |
| UN IDs | UN 1251 6.1/PG 1 |
| WGK Germany | 3 |
| RTECS | EM9800000 |
| FLUKA BRAND F CODES | 8-10-19-23 |
| TSCA | Yes |
| HS Code | 29141990 |
| Hazard Class | 6.1 |
| Packing Group | I |
Acetone, methylene- - Nature
Open Data Verified Data
colorless liquid, with a strong spicy taste, irritating. Flammable, relative density 0. 8407 (25 ℃), refractive index 1.4086 (20 ℃), boiling point 81.4 ℃, flash point -6. 67 (closed Cup). Soluble in water, methanol, ethanol, ether, acetone and acetic acid, slightly soluble in hydrocarbon compounds. A binary azeotrope is formed with water and has a azeotropic point of 75 °c (101 kPa) (12% water).
Last Update：2024-01-02 23:10:35
Acetone, methylene- - Preparation Method
Open Data Verified Data
acetone is condensed with formaldehyde in the presence of caustic soda, dehydrated to obtain a crude product, and then purified to obtain a pure product.
Last Update：2022-01-01 10:17:06
Acetone, methylene- - Use
Open Data Verified Data
It is used as an alkylating agent and an intermediate for synthesizing steroids and vitamin A, etc. It is also used as a polymerization monomer to prepare an anionic resin.
Last Update：2022-01-01 10:17:07
Acetone, methylene- - Safety
Open Data Verified Data
- inhalation of vapors can cause wheezing, bronchitis, and pulmonary edema. Skin contact will produce spots and can be absorbed through the skin poisoning. Small rodents oral LDso is 15~30mg/kg.
- This product is packed in 160kg round iron drum, 160kg ± 0.1kg per barrel.
Last Update：2022-01-01 10:17:07
Acetone, methylene- - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| purpose | is used as monomer in polymerization reaction to prepare anion resin, can also be used as alkylating agents and synthetic steroids and vitamin A intermediates The product has a strong reaction ability, used as a monomer polymer, preparation of anionic resin, film emulsifier; they are also useful as alkylating agents and intermediates in the synthesis of steroids and vitamin A. |
| production method | methyl vinyl ketone is prepared by condensing acetone with formaldehyde to obtain acetoethanol and dehydrating it in the presence of oxalic acid. The formaldehyde solution and acetone are mixed at 1:30 into the pipeline reactor (temperature 51-53 ℃), the flow rate is controlled, the reaction residence time is maintained for 3-4min, and the reaction solution is transferred to the reaction tank containing lemon-acetone, after refluxing for 10min, acetone was recovered, water was distilled off, oxalic acid was added for dehydration, a small amount of hydroquinone was added, and the azeotropic liquid of methyl ketene and water was obtained by atmospheric distillation. After salting out with refined salt, the layers were separated into layers, the organic layer was dehydrated with calcium chloride, hydrogenated to rectification, and the 80-83 ° C. Fraction was collected as methyl ketene in a yield of 42%. In addition, methyl vinyl ketone can also be obtained from the hydration of vinyl acetylene by using a sulfate of mercury, silver, copper and the like as a catalyst. |
| category | flammable liquid |
| toxicity grade | highly toxic |
| Acute toxicity | oral-rat LD50:30 mg/kg; Oral-mouse LD50: 33 mg/kg |
| flammability hazard characteristics | in case of fire, high temperature, oxidant flammable; high fever releases toxic and irritating smoke |
| storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; Stored separately from oxidants and acids |
| extinguishing agent | dry powder, dry powder, carbon dioxide, foam |
| Occupational Standard | SEL 0.1 mg/m3 |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 21:01:54
